Efficacy of cycloferon in the treatment and prevention of influenza and acute respiratory infections in children and teenagers
Abstract
Two hundred and fourteen children and teenagers aged 4 to 18 years were examined in a period of high incidence of influenza and acute respiratory viral infections (ARVI); of them 108 persons received a total of 4—5 cycloferon cycles in an age-adjusted dosage for 10 days for the complex prevention of influenza and ARVI. For treatment, 33 patients of the same age with influenza and ARVI had cycloferon in an age-adjusted dosage once daily for 10 days. Cycloferon used for prevention caused a 5,44-fold reduction in the incidence of influenza and ARVI; the protection ratio was 81,6%. Cycloferon used in the combination therapy of influenza and ARVI made them milder, reduced the time of their clinical manifestation and the incidence of complications, and normalized the indicators of the blood cytokine profile.
Keywords
About the Authors
V. A. Tereshin
Lugansk State Medical University, Ukraine
Ukraine
Ukraine
Ya. A. Sotskaya
Lugansk State Medical University, Ukraine
Ukraine
Ukraine
O. V. Kruglova
Lugansk State Medical University, Ukraine
Ukraine
Ukraine
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Review
For citations:
Tereshin V.A., Sotskaya Ya.A., Kruglova O.V. Efficacy of cycloferon in the treatment and prevention of influenza and acute respiratory infections in children and teenagers. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2014;59(2):103-109. (In Russ.)
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