Interactive clinical case as a modern virtual educational method for differential diagnosis of proteinuria in children
https://doi.org/10.21508/1027-4065-2025-70-6-138-144
Abstract
The article demonstrates the possibility of using the case method for teaching the diagnosis of rare diseases. The virtual diagnosis is based on clinical observation of a child with hiluria (ICD code: R82.0), which is caused by the formation of a lymphoureteral fistula against the background of a malformation of the lymphatic ducts. The difficulties of differential diagnosis of chyluria are due to the fact that it can manifest itself as high-level proteinuria with a decrease in albumin, blood immunoglobulins and the development of edema, i.e. a symptom complex of nephrotic syndrome.
The authors have developed a web application that allows a trained doctor to walk through the stages of the virtual diagnostic process, at each of which it is necessary to analyze the information provided about the patient and make a decision: determine a plan for further examination, «refer» the patient for consultations with specialists, while forming diagnostic hypotheses. The program allows you to evaluate the correctness of the choice of the student’s course of action and explain the error in making the wrong decision. As a result of completing the case, an integral score is calculated and displayed on the screen — the sum of points for correct answers to the questions asked. Repeated passage of virtual diagnostics, as a rule, increases the quantitative criterion, and most importantly, helps to consolidate the knowledge necessary for proper diagnosis. The interactive clinical case can be used to improve the skills of pediatricians, as well as in the process of teaching medical students and clinical residents as an additional tool. The use of the interactive case in the educational process makes it possible to acquire the skills of differential diagnosis within the framework of the presented clinical observation, in particular, to pay attention to the nature of changes in the lipid profile of blood and the physical properties of urine, especially in the case of atypical complaints in the patient. In addition, the presence of a training module in an interactive program, including animation to explain the pathogenesis, allows you to replenish knowledge on many aspects of hiluria.
About the Authors
A. N. PutintsevRussian Federation
125412, Moscow
M. E. Aksenova
Russian Federation
125412, Moscow
N. M. Zaikova
Russian Federation
125412, Moscow
D. A. Nikolsky
Russian Federation
125412, Moscow
K. Ya. Gusev
Russian Federation
125412, Moscow
R. R. Akhmetnabiev
Russian Federation
125412, Moscow
References
1. Crowe S., Cresswell K., Robertson A., Huby G., Avery A., Sheikh A. The case study approach. BMC Med Res Methodol. 2011; 11: 100. DOI: 10.1186/1471-2288-11-100
2. Univadis International Medical Portal. Online learning. http://www.univadis.ru/e-learning#?f1=-1 \ Ссылка активна на: 15.05.2025
3. Interactive cases. University of Minnesota Medical School. https://med.umn.edu/dom/education/global-medicine/courses-certificates/online/interactive-cases \ Ссылка активна на: 15.05.2025
4. Interactive Medical Case: The New England Journal of Medicine. http://www.nejm.multimedia/interactive-medical-case \ Ссылка активна на: 15.05.2025
5. Medical educational portal of ANO DPO «Academy of Innovative Education». https://rumedo.ru \ Ссылка активна на: 15.05.2025
6. Electronic database of clinical case scenarios ClinCaseQuest. https://clincasequest \ Ссылка активна на: 15.05.2025
7. Putintsev A.N., Kursova T.S., Nikolsky D.A., Razzhivaykin A.Yu., Gusev K. Ya., Morozov S.L., et al. Virtual diagnostics of rare diseases: evaluation of the effectiveness of feedback-based learning. Pediatrics. Eastern Europe. 2023; 11(3): 327–337. (in Russ). DOI: 10.34883/PI.2023.3.003
8. Stainer V., Jones P., Juliebø S.Ø., Beck R., Hawary A. Chyluria: what does the clinician need to know? Ther Adv Urol. 2020; 12: 1756287220940899. Published 2020 Jul 16. DOI: 10.1177/1756287220940899
9. Lovrec Krstić T., Šoštarič K., Caf P., Žerdin M. The Case of a 15-Year-Old With Non-Parasitic Chyluria. Cureus. 2021; 13(8): e17388. Published 2021 Aug 23. DOI: 10.7759/cureus.17388
10. Kaul A., Bhadhuria D., Bhat S., Sharma R.K., Karoli R., Gupta A., Prasad N. Chyluria: a mimicker of nephrotic syndrome. Ann Saudi Med. 2012; 32(6): 593–595. DOI: 10.5144/0256-4947.2012.593
11. Interactive clinical case. https://edu.pedklin.ru/cases \ Ссылка активна на: 15.05.2025
Review
For citations:
Putintsev A.N., Aksenova M.E., Zaikova N.M., Nikolsky D.A., Gusev K.Ya., Akhmetnabiev R.R. Interactive clinical case as a modern virtual educational method for differential diagnosis of proteinuria in children. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2025;70(6):138-144. (In Russ.) https://doi.org/10.21508/1027-4065-2025-70-6-138-144
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