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Coinfection caused by hepatitis C virus and human pegivirus in an 11-year-old teenager with aplastic anemia
https://doi.org/10.21508/1027-4065-2026-71-2-110-113
Abstract
Chronic hepatitis C is an urgent problem for Russian healthcare, including in pediatric practice. Currently, this infection can be successfully treated with the use of direct antiviral drugs. However, in some cases, due to the common ways of infection, especially with hemotransfusions, there is an infection caused by the hepatitis C virus and human pegivirus, the role of which is still not completely clear. A clinical observation from our own practice demonstrates the effectiveness of glecaprevir/pibrentasvir in an 11-year-old coinfected patient who received multiple blood transfusions against hepatitis C virus while maintaining pegivirus replication, which may have negatively affected the course of concomitant hematological disease.
About the Authors
O. N. Kandoba
Research clinical institute of childhood
Russian Federation
Russian Federation
115093, Moscow
V. A. Greshnyakova
Federal Research and Clinical Center for Infectious Diseases ; Saint-Petersburg State Pediatric Medical University ; St. Petersburg State University
Russian Federation
Russian Federation
197022, St. Petersburg
194100, St. Petersburg
199106, St. Petersburg
S. G. Gorbunov
Research clinical institute of childhood ; Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
115093, Moscow
125993, Moscow
N. D. Odinaeva
Research clinical institute of childhood ; M.F. Vladimirsky Moscow Regional Research and Clinical Institute
Russian Federation
Russian Federation
115093, Moscow
129110, Moscow
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Review
For citations:
Kandoba O.N., Greshnyakova V.A., Gorbunov S.G., Odinaeva N.D. Coinfection caused by hepatitis C virus and human pegivirus in an 11-year-old teenager with aplastic anemia. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2026;71(2):110-113. (In Russ.) https://doi.org/10.21508/1027-4065-2026-71-2-110-113
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