Mitral valve prolapse in young athletes
https://doi.org/10.21508/1027-4065-2014-59-6-9-16
Abstract
The paper discusses the current literature data and the authors' ones on the accurate diagnosis of mitral valve prolapse and its role in an athletic population. A comparative analysis shows a substantial (as high as 4—9-fold) reduction in the average rate of both the prolapse and its complications when diagnostic criteria are changed. Among 500 athletes referred for echocardiographic examination in the past 2 years, the rate of mitral valve prolapse has been only 0,2%. Assessment of the role of the prolapse indicates that the valve regurgitation that can increase during exercise is of basic value; in this connection, it is expedient to carry out exercise echocardiography tests.
About the Authors
A. S. SharykinRussian Federation
N. E. Popova
Russian Federation
V. A. Badtieva
Russian Federation
E. V. Shilykovskaya
Russian Federation
Yu. M. Ivanova
Russian Federation
P. A. Subbotin
Russian Federation
References
1. Guy T.S. Hill AC. Mitral valve prolapse. Annu Rev Med 2012; 63: 277-292.
2. Disse S., Abergel E., Berrebi A. et al. Mapping of a first locus for autosomal dominant myxomatous mitral-valve prolapsed to chromosome 16pll.2-pl2.1. Am J Hum Genet 1999; 65: 1242-1251.
3. TrochuJ.-N., KyndtF., SchottJ.-J. etal. Clinical characteristics of a familial inherited myxomatous valvular dystrophy mapped to Xq28. J Am Coll Cardiol 2000; 35: 1890-1897.
4. Grande-Allen K.J., Griffin B.P., Ratliff KB. et al. Glycosaminoglycan profiles of myxomatous mitral leaflets and chordate parallel the severity of mechanical alterations. J Am Coll Cardiol 2003; 42: 271-277.
5. Adams D.H., Rosenhek R., Falk V. Degenerative mitral valve regurgitation: best practice revolution. Eur Heart J doi: 10.1093/eurheartj/ehq222.
6. Barlow J.B., Bosman C.K., Pocock W.A., Marchand J. Late systolic murmurs and non-ejection (mild-late) systolic clicks: an analysis of 90 patients. Br Heart J 1968; 30: 203—218.
7. Шарыкин А. С. Пролапс митрального клапана — изменения в критериях диагностики и варианты течения заболевания. Consilium medicum, приложение Педиатрия 2013; 2: 43—48. (Sharykin A.S. Mitral valve prolapse — changes in diagnostic criteria and variations of manifestation. Consilium medicum, suppl. Pediatrija2013; 2: 43—48).
8. Levine R.A., Triulzi M.O., Harrigan P., Weyman A.E. The relationship of mitral annular shape to the diagnosis of mitral valve prolapsed. Circulation 1987; 75: 756—767.
9. Freed L.A., Benjamin E.J., Levy D. et al. Mitral valve prolapse in the general population. The benign nature of echocardiographic features in the Framingham Heart Study. J Am Coll Cardiol 2002; 40: 1298-1304.
10. Weyman A.E., Sherrer-Crosbi M. Marian syndrome and mitral valve prolapsed. J Clinic Invest 2004; 114: 1543—1546.
11. Cheng Т. О., Barlow J.B. Mitral leaflet billowing and prolapsed. Its prevalence around the world. Angiology 1989; 40: 77—87.
12. Devereux R.B., Jones E.C., Roman M.J. et al. Prevalence and correlates of mitral valve prolapse in a population-based sample of American Indians: the strong heart study. Am J Med 2001; 111: 679-685.
13. Avierinos J-F., Brown R.D., Foley D.A. et al. Cerebral ischemic events after diagnosis of mitral valve prolapsed. A community-based study of incidence and predictive factors. Stroke 2003; 34: 1339-1345.
14. Yoshida K., Yoshikawa J., Shakudo M. et al. Color Doppler evaluation of valvular regurgitation in normal subjects. Circulation 1988; 78: 840-847.
15. Thomson J.D.R., Allen J., Gibbs J.I. Left sided valvar regurgitation in normal children and adolescents. Heart 2000; 83: 185-187.
16. Jeresaty R.M. Mitral valve prolapse: Definition and implications in athletes. J Am Coll Cardiol 1986; 7: 231—236.
17. HepnerA.D., Morrell H., Greaves S. et al. Prevalence of mitral valvar prolapse in young athletes. Cardiology in the Young 2008; 18: 402-404.
18. Wand O., Prokupetz A, Grossman A, Assa A. Natural history of mitral valve prolapse in military aircrew. Cardiology 2011; 118: 1:50—54.
19. Шарыкин АС, Шилыковская Е.В., Колесникова М.А. и др. Оценка систолической функции левого желудочка у детей-спортсменов в ответ на физическую нагрузку. Рос вестн перинатол и педиат 2010; 5: 83—89. (Sharykin A.S., Shilykovskaja E.V., Kolesnikova M.A. et al. Assessment of a left ventricular systolic function in young athletes at exercise. Ros vestnperinatal ipediat 2010; 5: 83—89.)
20. Stoddard M.F., Prince C.R., Dillon S. et al. Exercise-induced mitral regurgitation is a predictor of morbid events in subjects with mitral valve prolapse. JAm Coll Cardiol 1995; 25: 693—699.
21. Pecini R., Dalsgaard M., Moller D.V. et al. Moderate exercise does not increase the severity of mitral regurgitation due to mitral valve prolapse. Echocardiography 2010; 27: 9: 1031—1037.
Review
For citations:
Sharykin A.S., Popova N.E., Badtieva V.A., Shilykovskaya E.V., Ivanova Yu.M., Subbotin P.A. Mitral valve prolapse in young athletes. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2014;59(6):40-45. (In Russ.) https://doi.org/10.21508/1027-4065-2014-59-6-9-16