Anti-NMDA receptor encephalitis
https://doi.org/10.21508/1027-4065-2014-59-6-120-124
Abstract
Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis is an autoimmune central nervous system disease mediated by antibodies to certain subunit of the N-methyl-D-aspartate receptor and characterized by the development of severe psychiatric and neurological disorders in previously healthy children. The paper describes a clinical case in an 8-year-old female patient with this disease presenting with seizures, psychiatric symptoms and behavioral problems. Then the disease progressed to dyskinesis and memory and speech disorders. The final diagnosis of anti-NMDA receptor encephalitis was made after identifying anti-NMDA receptor antibodies in the cerebral spinal fluid.
About the Authors
A. V. Surovtseva
Research Institute of Children's Infections, Saint Petersburg
Russian Federation
Russian Federation
N. V. Skripchenko
Research Institute of Children's Infections, Saint Petersburg
Russian Federation
Russian Federation
G. P. Ivanova
Research Institute of Children's Infections, Saint Petersburg
Russian Federation
Russian Federation
N. F. Pulman
Research Institute of Children's Infections, Saint Petersburg
Russian Federation
Russian Federation
A. I. Konev
Research Institute of Children's Infections, Saint Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Surovtseva A.V., Skripchenko N.V., Ivanova G.P., Pulman N.F., Konev A.I. Anti-NMDA receptor encephalitis. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2014;59(6):103-105. (In Russ.) https://doi.org/10.21508/1027-4065-2014-59-6-120-124
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