Clinical efficacy of goat's milk-based formulas containing prebiotics in the feeding of infants with functional indigestion
https://doi.org/10.21508/1027-4065-2014-59-6-142-144
Abstract
The clinical efficacy of adapted Nanny 1 and 2 formulas containing prebiotics in the diet of infants with functional indigestion during the first year of life was evaluated. A total of 120 babies during the first year of fife were followed up. Of them, 27 patients within the first 5 months of life received the formula Nanny 1 with prebiotics, which was replaced by Nanny 2 with prebiotics in 33 infants during 5,5—6 months of fife (a study group). A comparison group consisted of 60 formula-fed infants of the same age who switched to the formula Nanny classic without prebiotics. During the use of Nanny goat's milk based formulas for 1 to 3 months, there was a reduction or cessation of the symptoms of functional ingestion, improvement in stool pattern, and a decline in the number of infants with disordered intestinal microflora. The values of secretory IgA increased and the level of C-reactive protein decreased in the coprofiltrates, suggesting that there was increased higher local intestinal immunity and reduced inflammation. The most pronounced positive effect was observed in the babies who were fed the formulas containing prebiotics. Thus, Nanny 1 and 2 formulas with prebiotics for feeding babies during the first year of life show good tolerability, relieve the symptoms of functional indigestion, and prevent enteric dysbiosis and chronic eating disorders.
About the Authors
S. N. Denisova
N.I. Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
M. Yu. Belitskaya
G.N. Speransky City Children's Clinical Hospital Nine, Moscow
Russian Federation
Russian Federation
T. B. Sentsova
Research Institute of Nutrition, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
V. A. Revyakina
Research Institute of Nutrition, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
L. I. Ilienko
N.I. Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
S. V. Bogdanova
City Polyclinic Two Hundred and Nineteen, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Denisova S.N., Belitskaya M.Yu., Sentsova T.B., Revyakina V.A., Ilienko L.I., Bogdanova S.V. Clinical efficacy of goat's milk-based formulas containing prebiotics in the feeding of infants with functional indigestion. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2014;59(6):114-119. (In Russ.) https://doi.org/10.21508/1027-4065-2014-59-6-142-144
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