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Experience with cytoflavin used in extremely premature infants

https://doi.org/10.21508/1027-4065-2016-61-2-100-104

Abstract

To reduce the damaging action of hypoxia and to correct severe metabolic and cardiac disorders in critically ill premature newborn infants, metabolic therapy with cytoflavin was studied in extremely premature infants (33 and 25 babies in a study group and a comparison one, respectively).

The use of this drug in extremely low and very low birthweight babies with posthypoxic myocardial damage and severe metabolic disorders was found to lead to normalization of acid-base balance within 24 hours after treatment initiation. During the therapy, there was a marked cardiocytoprotective effect and no increase in the degree of intragastric bleedings.

About the Authors

I. V. Vinogradova
Presidential Perinatal Center
Russian Federation


A. N. Belova
Presidential Perinatal Center
Russian Federation


M. V. Krasnov
I.N. Ulyanov Chuvash State University, Ministry of Health and Social Development of Chuvashia
Russian Federation


N. N. Emeliyanova
I.N. Ulyanov Chuvash State University, Ministry of Health and Social Development of Chuvashia
Russian Federation


T. G. Bogdanova
Министерство здравоохранения и социального развития Чувашской Республики
Russian Federation

к.м.н., доцент, зам. министра,

428000 Чебоксары, Президентский бульвар, д. 17



D. A. Vinogradov
I.N. Ulyanov Chuvash State University, Ministry of Health and Social Development of Chuvashia
Russian Federation


V. S. Vinogradova
I.N. Ulyanov Chuvash State University, Ministry of Health and Social Development of Chuvashia
Russian Federation


References

1. Perlman J.M. Neurology: neonatology questions and controversies. Saunders, Elsevier, 2008; 225.

2. Володин Н.Н., Рогаткин С.О., Людовская Е.В. Лечение детей, перенесших перинатальную гипоксию в период ранней неонатальной адаптации. Вопр гинекол, акуш и перинатол 2005; 1: 20–25. (Volodin N.N., Rogatkin S.O., Ljudovskaja E.V. Treatment of children with perinatal hypoxia during the early neonatal adaptation. Vopr ginekol, akush i perinatol 2005; 1: 20–25.)

3. Рогаткин С.О. Диагностика, профилактика и лечение перинатальных постгипоксических поражений центральной нервной системы у ново рожденных и детей ран него возраст а. Автореф. дисс. … докт. мед. наук. М 2012; 44. (Rogatkin S.O. Diagnosis, prevention and treatment of perinatal posthypoxic lesions of the central nervous system in children and new born his age and injuries. Avtoref. diss. … dokt. med. nauk. M 2012; 44.)


Review

For citations:


Vinogradova I.V., Belova A.N., Krasnov M.V., Emeliyanova N.N., Bogdanova T.G., Vinogradov D.A., Vinogradova V.S. Experience with cytoflavin used in extremely premature infants. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2016;61(2):100-104. (In Russ.) https://doi.org/10.21508/1027-4065-2016-61-2-100-104

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ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)