Mitochondrial cardiomyopathies
https://doi.org/10.21508/1027-4065-2016-61-3-22-30
Abstract
The paper considers the problem of diagnosing the heterogeneous forms of mitochondrial cardiomyopathies associated with impaired oxidative phosphorylation and decreased activity of the mitochondrial electron transport system due to mutations in mitochondrial or nuclear DNA genes. It is emphasized that mitochondrial cardiomyopathies rarely present as an isolated myocardial lesion and more frequently serve as a manifestation of multisystem disease. The paper provides the characteristics of cardiomyopathies in some mitochondrial syndromes and shows the possibilities of treating this disease.
About the Authors
I. V. Leontyeva
Academician Yu.E. Veltishchev Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University
Russian Federation
Moscow
Russian Federation
Moscow
E. A. Nikolaeva
Academician Yu.E. Veltishchev Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Leontyeva I.V., Nikolaeva E.A. Mitochondrial cardiomyopathies. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2016;61(3):22-30. (In Russ.) https://doi.org/10.21508/1027-4065-2016-61-3-22-30
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