Choice of vasoconstrictors for children with rhinosinusitis
https://doi.org/10.21508/1027-4065-2016-61-3-92-96
Abstract
The paper highlights the principal items of use of decongestants in the treatment of rhinosinusitis in children. It analyzes the advantages and disadvantages of all classes of decongestants and their role in the pathogenetic therapy of rhinosinusitis. The role of complex vasoconstrictors including excipients (certain components of essential oils) is defined, by using Lasolvan®Rhino as an example. The efficient and timely therapy of acute rhinitis in children can considerably reduce the frequency of complications and improve a child’s health, helping restore normal eating and sleep. Since the earliest treatment is of the greatest importance in the therapy of acute rhinosinusitis, emphasis is placed on decongestants within the first days of the disease. The decongestant Lasolvan®Rhino (Boehringer Ingelheim) fully meets the goals of treatment for acute rhinosinusitis in children over 6 years of age as an effective, reliable, and safe agent, as evidenced by clinical trials.
About the Authors
T. I. Garashchenko
Otorhinolaryngology Research and Clinical Center, Federal Biomedical Agency of Russia
Russian Federation
Moscow
Russian Federation
Moscow
N. E. Boikova
Otorhinolaryngology Research and Clinical Center, Federal Biomedical Agency of Russia
Russian Federation
Moscow
Russian Federation
Moscow
E. M. Zelenkin
Otorhinolaryngology Research and Clinical Center, Federal Biomedical Agency of Russia
Russian Federation
Moscow
Russian Federation
Moscow
References
1. Гаращенко Т.И. Выбор сосудосуживающих препаратов при риносинуситах у детей. Тез. 16 съезда педиатров России «Актуальные проблемы педиатрии». Consilium medicum 2009; 8–15. (Garashhenko T.I., The choice of vasoconstrictor drugs during rhinosinusitis in children. Consilium medicum, 2009; 8–15.)
2. Гаращенко Т.И., Страчунский Л.С. Антибактериальная терапия ЛОР заболеваний в детском возрасте. В кн. Детская оториноларингология. Под ред. М.Р. Богомильского, В.Р. Чистяковой. М., Медицина, 2005; 299–317. (Garashhenko T.I., Strachunskij L.S. Antibiotic therapy of ENT diseases in children. In. Children’s otolaryngology. M.R. Bogomil’skij, V.R. CHistyakova (eds). Moscow: Meditsina, 2005; 299–317.)
3. Гаращенко Т.И. Диагностическая и лечебная эндоскопия в детской оториноларингологии. В кн. Детская оториноларингология. Под ред. М.Р. Богомильского, В.Р. Чистяковой. М., Медицина, 2005; 338–400. (Garashhenko T.I., Antibiotic therapy of ENT diseases in children. In. Children’s otolaryngology. M.R. Bogomil’skij, V.R. Chistyakova (eds). Moscow: Medicina, 2005; 338–400.)
4. Гаращенко Т.И., Стребкова О.А. Возрастные особенности эндоскопической внутриносовой хирургии осложненных риносинуситов у детей. Рос Ринол 2002; 2: 179–182. (Garashhenko T.I., Strebkova O.A. Age features of intranasal endoscopic surgery complicated rhinosinusitis in children. Ros Rinol 2002; 2: 179–182.)
5. Passali D., Salerni L., Passali G.C., Passali F.M. Nasal decongestants in the treatment of chronic nasal obstruction: efficacy and safety of use. Expert Opinion on Drug Safety 2006; 5: 6: 783–790.
6. Гаращенко Т.И. Пороки развития внутриносовых структур и риносинуситы у детей. Вестн оторинолар 1996; 5: 15–18. (Garashhenko T.I., Malformations of the intranasal structures and rhinosinusitis in children. Vestn otorinolar 1996; 5: 15–18.)
7. Гаращенко Т.И., Богомильский М.Р., Стребкова О.А. Алгоритмы рациональной антибиотикотерапии осложненных риносинуситов удетей. Рос Ринол 2002; 2: 108–111.
8. (Garashhenko T.I., Bogomil’skij M.R., Strebkova O.A. Algorithms for rational antibiotic therapy of complicated rhinosinusitis in children. Ros Rinol 2002; 2: 108–111.)
9. Карпова Е.П., Тулупов Д.А. К вопросу о безопасности и эффективности назальных сосудосуживающих препаратов в педиатрической практике. Вопр практич педиатрии 2010; 5: 5: 1–4. (Karpova E.P., Tulupov D.A. On the question of the safety and efficacy of nasal vasoconstrictor drugs in pediatric practice. Vopr praktich pediatrii 2010; 5: 5: 1–4.)
10. Тарасова Г.Д. Альтернативная терапия некоторых форм ринита. Пульмонол и оториноларингол 2011; 3: 14–21. (Tarasova G.D. Alternative treatment of some forms of rhinitis. Pul’monol otorinolaringol 2011; 3: 14–21.)
11. Яблонева В.Н., Гаращенко Т.И. Использование деконгестантов в детской оториноларингологии. Детская оторинолар 2001; 1: 48–50. (Jabloneva V.N., Garashhenko T.I. The use of decongestants in pediatric otolaryngology, Detskaja otorinolar 2001; 1: 48–50.)
12. Нурмухаметов Р.А. Сосудосуживающие средства (деконгестанты). Consilium medicum 2001; 1: 1: 21–23. (Nurmuhametov R.A. Decongestants Consilium medicum 2001; 1: 1: 21–23.)
13. Corboz M.R., Rivelly M.A., Varty L. et al. Pharmacological characterization of postjuctional alpha-adrenoreceptors in human nasal mucosa. Am J Rhinol 2005; 19: 5: 495–502.
14. Lacroix J.S. Adrenergic and non-adrenergic mechanisms in sympathetic vascular control of the nasal mucosa. Acta Physiol Scand 1989; 136: 581: 1–63.
15. Final monograph for OTC nasal decongestant drug products; Final rule. Fed Reg 1994; 59: 43386–43412.
16. Инструкция по применению лекарственного препарата для медицинского препарата Лазолван® Рино. 2016; http://www.grls.rosminzdrav.ru
17. Katona G., Sultész M., Farkas Z. et al. Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial. Clin Transl Allergy 2015; 5: 38.
Review
For citations:
Garashchenko T.I., Boikova N.E., Zelenkin E.M. Choice of vasoconstrictors for children with rhinosinusitis. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2016;61(3):124-131. (In Russ.) https://doi.org/10.21508/1027-4065-2016-61-3-92-96
Views:
880
Email this article 