Features of the cardiovascular system in babies born with different types of intrauterine growth restriction
https://doi.org/10.21508/1027-4065-2017-62-2-30-38
Abstract
Based on the data of clinical and anamnestic examination, cardiointervalography, electrocardiography, and Doppler echocardiography, the investigators examined the features of the cardiovascular system in children born by women with compromised somatic and gynecological histories in the outcome of complicated pregnancy. Groups 1 and 2 included 72 and 69 infants with and without fetal growth restriction, respectively. Group 1 comprised Subgroup 1a of 57 infants with asymmetrical intrauterine growth restriction and Subgroup 1b of 15 children with symmetrical one; of them there were 13 and 2 infants with hypoplastic and dysplastic types. Apparently healthy infants born by apparently healthy mothers in the outcome of physiological pregnancies made up Group 3 (n = 25).
There is proof that there are significantly important features of autonomic regulation of cardiac activity and morphofunctional characteristics of the heart. The infants with symmetrical intrauterine growth retardation, unlike those with asymmetrical one, were observed to have impaired autonomic regulation of cardiac activity, which was less obvious at birth, deteriorating over time. At birth, the babies had morphological features of the heart and a greater frequency of functioning of fetal communications. Impaired myocardial metabolic processes prevailed within the first month of life and there was a large frequency of changes similar to those in hypertrophic cardiomyopathy by the end of the first half of life.
The featuresrevealed in the infants with different types of intrauterine growth restriction require electrocardiographic and ultrasound examinations, a pediatric cardiologist’s consultations at a maternity hospital, and a subsequent personalized follow-up with corrective measures at an outpatient setting.
About the Authors
L. V. Kozlova
Federation Council, Federal Assembly of the Russian Federation
Russian Federation
Moscow
Russian Federation
Moscow
D. O. Ivanov
Saint Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
V. V. Derevtsov
V.A. Almazov North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation;
N.A. Semashko Children’s Center for Diagnosis and Treatment
Russian Federation
Russian Federation
Saint Petersburg;
Moscow
N. F. Priyma
V.A. Almazov North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
References
1. Ветеркова З.А., Евстифеева Г.Ю., Альбакасова А.А. Морфофункциональные особенности сердечной деятельности у детей, рожденных с задержкой внутриутробного развития в различные возрастные периоды. Интеллект. Инновации. Инвестиции 2012; 1: 124–128. [Veterkova Z.A., Evstifeeva G. Yu., Al’bakasova A.A. Morphofunctional features of cardiac activity in prenatal development delay children at different ages. Intellekt. Innovatsii. Investitsii 2012; 1: 124–128. (in Russ)].
2. Иванов Д.О., Козлова Л.В., Деревцов В.В. Вегетативная дисфункция и адаптационно-резервные возможности у детей, рожденных с внутриутробной задержкой роста, в первом полугодии жизни. Педиатр 2016; 4(7): 77–89. [Ivanov D.O., Kozlova L.V., Derevcov V.V. Autonomic nervous system dysfunction and adaptive reserves potential in infants born with intrauterine growth restriction in the first six months of life. Pediatr 2016; 4(7): 77–89. (in Russ)].
3. Козлова Л.В., Иванов Д.О., Деревцов В.В., Прийма Н.Ф. Изменения сердечно-сосудистой системы у детей, рожденных с задержкой роста плода, в первом полугодии жизни. Рос вестн перинатол и педиатр 2016; 6(61): 59–67. [Kozlova L.V., Ivanov D.O., Derevcov V.V., Prijma N.F. Changes in the cardiovascular system of infants born with intrauterine growth restriction in the first six months of life. Ros vestn perinatol i pediatr 2016; 6(61): 59–67. (in Russ)].
4. Марковский В.Д., Мирошниченко М.С., Плитень О.Н. Патоморфология сердца плодов и новорожденных при различных вариантах задержки внутриутробного развития. Перинатол и педиатр 2012; 2(50): 075. [Markovskiy V.D., Miroshnichenko M.S., Pliten’ O.N. Pathomorphology of the fetus and newborn heart in various kinds of prenatal development delay. Perinatol i pediatr 2012; 2(50): 075. (in Russ)].
5. Мирошниченко М.С. Патогистологические особенности сердца и органов мочевыделительной системы у плодов и новорожденных с задержкой внутриутробного развития. Украiнський журнал нефрологii та дiалiзу 2013; S3: 77–82. [Miroshnichenko M.S. Pathohistological features of the heart and urinary system in fetuses and newborns with prenatal development delay. Ukrains’kiy zhurnal nefrologii ta dializu 2013; S3: 77–82. (in Ukr)].
6. Ожегов А.М., Трубачев Е.А., Петрова И.Н. Мозговая и сердечная гемодинамика у детей первого года жизни, родившихся с задержкой внутриутробного развития. Детская больница 2012; 48(2): 34–36. [Ozhegov A.M., Trubachev E.A., Petrova I.N. Brain and heart hemodynamics in children in the first year of life with prenatal development delay. Detskaya bol’nitsa 2012; 48(2): 34–36. (in Russ)].
7. Петрова И.Н. Особенности неонатального периода у доношенных детей с задержкой внутриутробного развития. Врач-аспирант 2013; 56(1.1): 218–226. [Petrova I.N. Features of the neonatal period in full-time infants with prenatal development delay. Vrach-aspirant 2013; 56(1.1): 218–226. (in Russ)].
Review
For citations:
Kozlova L.V., Ivanov D.O., Derevtsov V.V., Priyma N.F. Features of the cardiovascular system in babies born with different types of intrauterine growth restriction. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2017;62(2):30-38. (In Russ.) https://doi.org/10.21508/1027-4065-2017-62-2-30-38
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