Vitamin K1 levels in the umbilical cord blood of neonates in Arkhangelsk
https://doi.org/10.21508/1027-4065-2017-62-2-49-53
Abstract
The optimal course of biochemical processes needs adequate dietary intake of vitamins involved in the body’s metabolic reactions. The basis for the pathogenesis of neonatal hemorrhagic disease is deficiency of vitamin K, the level of which in the North-Western Region of Russia was estimated for the first time.
Objective: to measure umbilical cord blood vitamin K1 levels in newborn infants.
Methods. Forty full-term newborns were examined. Vitamin K1 levels were determined using high performance liquid chromatography-tandem mass spectrometry.
Results. The mean umbilical blood cord level of vitamin K1 was very low and amounted to 0.05 (<0.03; 0.15) µg/l. This study revealed no relationship between the level of the above trace element and neonatal sex (p=0,854), maternal age (p=0,913), abortions (p=0,568), threatened abortion (p=0,109), smoking (p=0,923).
Conclusion. The umbilical cord blood concentration of vitamin K1 in the newborns was found to be very low, which increases the risk of hemorrhagic disease and requires exogenous replenishment of the above vitamin after birth.
About the Authors
L. G. Kiseleva
Northern State Medical University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
G. N. Chumakova
Northern State Medical University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
A. G. Soloviev
Northern State Medical University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
O. A. Kharkova
Northern State Medical University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
D. S. Kosyakov
Arktika Center for Collective Use of Scientific Equipment, M.V. Lomonosov Northern (Arctic) Federal University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
N. V. Ulyanovsky
Arktika Center for Collective Use of Scientific Equipment, M.V. Lomonosov Northern (Arctic) Federal University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
E. M. Gryzunova
Northern State Medical University
Russian Federation
Arkhangelsk
Russian Federation
Arkhangelsk
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Review
For citations:
Kiseleva L.G., Chumakova G.N., Soloviev A.G., Kharkova O.A., Kosyakov D.S., Ulyanovsky N.V., Gryzunova E.M. Vitamin K1 levels in the umbilical cord blood of neonates in Arkhangelsk. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2017;62(2):49-53. (In Russ.) https://doi.org/10.21508/1027-4065-2017-62-2-49-53
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