Features of immunological status in young children, with spastic forms of infantile cerebral paralysis
https://doi.org/10.21508/1027-4065-2017-62-5-153-157
Abstract
In order to analyze the prognostic significance of the clinical and immunologic indices of central nervous system (CNS) lesions of the perinatal period, 135 children with an early residual stage of infantile cerebral paralysis (cerebral paralysis) were examined. A statistically significant increase in functional phagocytic activity, tumor necrosis factor-α (TNF-α) level in blood serum and oral fluid (p≤0.01 and p<0.05, respectively) in children with periventricular leukomalacia in spastic forms of infantile cerebral paralysis. Neuroimmunological parameters of blood serum and oral fluid can be used as criteria for diagnosing the severity of structural and morphological changes in the central nervous system and predicting cerebral disorders in children with an outcome in infantile cerebral paralysis.
About the Authors
D. D. Gainetdinova
Kazan State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
L. Z. Afandieva
Children’s Republican Clinical Hospital, Ministry of Health of the Republic of Tatarstan
Russian Federation
Russian Federation
R. F. Hakimova
Kazan State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Gainetdinova D.D., Afandieva L.Z., Hakimova R.F. Features of immunological status in young children, with spastic forms of infantile cerebral paralysis. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2017;62(5):153-157. (In Russ.) https://doi.org/10.21508/1027-4065-2017-62-5-153-157
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