Проблемы современной диагностики и лечения дилатационной кардиомиопатии у детей
https://doi.org/10.21508/1027-4065-2018-63-2-7-15
Аннотация
Представлены данные об этиологии дилатационной кардиомиопатии у детей (постмиокардитическая, метаболическая, ассоциированная с нервно-мышечной патологией, идиопатическая). Освещены генетические аспекты заболевания, описан широкий спектр мутаций в генах, кодирующих белки различных структур кардиомиоцита (саркомерного комплекса, цитоскелета, Z-дисков, митохондрий), различные варианты наследования. Подчеркнута необходимость ранней диагностики метаболических кардиомиопатий. Представлены критерии неблагоприятного прогноза. Освещены современные подходы к медикаментозному и хирургическому лечению дилатационной кардиомиопатии.
Ключевые слова
Об авторе
И. В. Леонтьева
ОСП «Научно-исследовательский клинический институт педиатрии имени академика Ю.Е. Вельтищева» ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава Российской Федерации, Москва
Россия
д.м.н., проф., главный научный сотрудник отдела детской кардиологии и аритмологии
Россия
д.м.н., проф., главный научный сотрудник отдела детской кардиологии и аритмологии
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Рецензия
Для цитирования:
Леонтьева И.В. Проблемы современной диагностики и лечения дилатационной кардиомиопатии у детей. Российский вестник перинатологии и педиатрии. 2018;63(2):7-15. https://doi.org/10.21508/1027-4065-2018-63-2-7-15
For citation:
Leontyeva I.V. Problems of modern diagnostics and treatment of dilated cardiomyopathy in children. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(2):7-15. (In Russ.) https://doi.org/10.21508/1027-4065-2018-63-2-7-15
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