Патология сердечно-сосудистой системы у детей с хроническими болезнями почек: эпидемиология, факторы риска, патогенез
Аннотация
Кардиоваскулярные болезни – частое осложнение хронических заболеваний почек и лидирующая причина смертности больных с терминальной почечной недостаточностью. Поражение сердечно-сосудистой системы при хронических болезнях почек обусловлено ранним формированием традиционных факторов (артериальная гипертензия, дислипидемия) и наличием нефрогенных факторов кардиоваскулярного риска (анемия, диспротеинемия, нарушение фосфорно-кальциевого обмена). Нефрогенные факторы риска определяются характером патологии почек и степенью нарушения почечных функций. Кардиоваскулярные изменения включают ремоделирование сосудистой стенки и миокарда, приводя со временем к нарушению их функции. В статье рассмотрены современные представления о патогенезе развития сердечно-сосудистой патологии у больных с хроническими болезнями почек.
Об авторе
М. Е. Аксенова
Научно-исследовательский клинический институт педиатрии ГБОУ ВПО «РНИМУ им. Н.И. Пирогова», Москва
Россия
Россия
в.н.с. отделения наследственных и приобретенных болезней почек
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Рецензия
Для цитирования:
Аксенова М.Е. Патология сердечно-сосудистой системы у детей с хроническими болезнями почек: эпидемиология, факторы риска, патогенез. Российский вестник перинатологии и педиатрии. 2015;60(2):22-28.
For citation:
Aksenova M.E. Cardiovascular system diseases in children with chronic kidney diseases: Epidemiology, risk factors, pathogenesis. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2015;60(2):22-28. (In Russ.)
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