BRONCHOECTATIC DISEASE IN CHILDREN
https://doi.org/10.21508/1027-4065-2018-63-5-29-35
Abstract
Bronchiectasis is characterized by a chronic and abnormal expansion of the respiratory tract; it is caused by impaired clearance of various microorganisms and recurrent infection. The cause of 26%–53% cases of bronchiectasis is unknown, which means that their etiology and pathogenesis are to be studied. This review summarizes current knowledge of epidemiology, pathophysiology, clinical features and management of children with bronchoectatic disease. Recent data allow us to improve our understanding of this heterogeneous disease, for example, the role of the interaction of the immune system and microbiota in the pathogenesis of bronchoectatic disease.
About the Authors
А. А. Stepanov
Pirogov Russian National Research Medical University.
Russian Federation
Russian Federation
A. R. Badalyan
Pirogov Russian National Research Medical University.
Russian Federation
Russian Federation
A. O. Melnikova
Pirogov Russian National Research Medical University.
Russian Federation
Russian Federation
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Review
For citations:
Stepanov А.А., Badalyan A.R., Melnikova A.O. BRONCHOECTATIC DISEASE IN CHILDREN. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(5):29-35. (In Russ.) https://doi.org/10.21508/1027-4065-2018-63-5-29-35
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