OPPORTUNITIES OF EARLY TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTION IN CHILDREN
Abstract
Purpose: to evaluate effectiveness of Oscillococcinum in the treatment of acute respiratory viral infections (ARVI) in children of different age groups.
We observed 140 children from 1 to 14 years with mild to moderate-severe acute respiratory viral infection. 80 children (Group 1) were treated with Oscillococcinum, 60 children (Group 2) were treated symptomatically. Group 1 was divided into Subgroup 1А (40 children of 1–5 years old) and Subgroup 1B (40 children >5–14 years old). Group 2 was divided into Subgroup 2А (30 children of 1–5 years old) and Subgroup 2B (30 children >5–14 years old). The follow-up period was 7–10 days. Clinical efficacy was assessed by the severity of ARVI symptoms in scores from 0 to 2. All adverse events of the therapy were recorded. Also we evaluated disappearance of ARVI symptoms within 48 hours after the beginning of the therapy.
Results: Oscillococcinum reduced the duration of ARVI in children of different age groups. During the first two days the symptoms of acute respiratory viral infection disappeared in 13 (16.3%) children of Group 1 receiving oscilococcinum and in 4 (6.7%) patients from Group 2 (OR = 2.7, 95 % CI 0.8–8.8, p <0.001).
Conclusion: Oscillococcinum is an effective and safe drug to treat ARVI in children of different age groups.
About the Authors
N. A. Gеppe
Sechenov First Moscow State Medical University.
Russian Federation
Russian Federation
N. A. Krylova
Sechenov First Moscow State Medical University.
Russian Federation
Russian Federation
T. I. Eliseeva
Privolzhsky Research Medical University.
Russian Federation
Russian Federation
E. N. Tyurina
Sechenov First Moscow State Medical University.
Russian Federation
Russian Federation
E. A. Yablokova
Sechenov First Moscow State Medical University.
Russian Federation
Russian Federation
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For citations:
Gеppe N.A., Krylova N.A., Eliseeva T.I., Tyurina E.N., Yablokova E.A. OPPORTUNITIES OF EARLY TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTION IN CHILDREN. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(5):103-107. (In Russ.)
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