Hypophosphatasia in children: Diagnostic problems and treatment prospects
Abstract
The paper gives up-to-date information on hypophosphatasia in children. It represents the results of genetic studies, the pathogene-sis, clinical manifestations, classification, treatment, and prevention of the disease. Particular emphasis is placed on whether clinical trials of novel biological agents for the pathogenetic therapy of hypophosphatasia (enzyme replacement therapy) may be conducted.
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Review
For citations:
Novikov P.V. Hypophosphatasia in children: Diagnostic problems and treatment prospects. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2015;60(1):23-26. (In Russ.)
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