Trends in morbidity rates and developmental outcomes by 3 years of life in premature children followed up in a specialized center
Abstract
This article analyzes morbidity rates and developmental outcomes in very premature infants in the first 3 years of life. A total of 2860 premature infants, including 1386 infants with birth weight less than 1500 g, in the 1997–2008 and 2008–2014 periods were examined. In the past 10 years, improvement of nursing tactics for very premature infants has led to a considerable reduction in the rate of prematurity-related diseases: chronic respiratory diseases, severe neurological disorders, and severe retinopathy, as well as to an improvement of physical psychomotor development indices by 3 years of life. Emphasis is laid on the importance of a three-step follow-up system in timely detecting a disease and defining the optimal tactics of early intervention.
About the Authors
E. S. Sakharova
Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
E. S. Keshishian
Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
G. A. Alyamovskaya
Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
References
1. Байбарина Е.Н., Верещинский А.М., Горелик К.Д. и др. Диагностика и лечение респираторного дистресс-синдрома (РДС) недоношенных. Проект методических рекомендаций Российской ассоциации специалистов перинатальной медицины (РАСПМ). Интенсивная терапия 2007; 2: http://icj.ru/journal/number-2-2007/114-diagnostika-i-lechenie- respiratornogo-distress-sindroma-rds-nedonoshennyh. html. (Baybarina E.N., Vereschinskiy A.M., Gorelik K.D. et al The diagnostics and treatment of respiratory- distress syndrome in premature infants. The Project of guide of Russian associa tion of perinatal medicine. (RASPM). Intensivnaya terapiya 2007, 2, http://icj.ru/journal/number-2-2007/114-diagnostika- i-lechenie-respiratornogo-distress-sindroma-rds-nedonoshennyh. html)
2. Adair L.S. Developing world perspective: the importance of growth for short term health. Nestle Nutr Inst Workshop Ser Pediatr Program 2010; 65: 71–83.
3. Ehrenkranz R.A., Dusick A.M.,Vohr B.R. et al. Growth in neonatal intensive care unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants. Pediatrics 2006; 117: 1253–1261.
4. Журба Л.Т., Мастюкова Е.М. Нарушение психомоторного развития детей первого года жизни. М: Медицина 1981; 272. (Gurba L.T., Mastyukova E.M. Psychomotor development disturbance in children of first year of life. Moscow: Medicina 1981; 272.)
5. Сахарова Е.С. Становление психомоторных функций и прогнозирование отклонений в развитии глубоконедоношенных детей на 1–2-м году жизни: Автореф. дисс. … канд. мед. наук. М 2003; 27. (Sakharova E.S. The establishment of psychomotor functions and predictors of developmental disturbances in very premature infants in first 2 years of life: Avtoref dis. … kand. med. nauk. Moscow 2003; 27.)
6. Casey P.H., Whiteside-Mansell L., Barrett K. et al. Impact of prenatal and/or postnatal growth problems in low birth weight preterm infants on school-age outcomes: an 8-year longitudinal evaluation. Pediatrics 2006; 118: 3: 1078–1086.
7. Cooke R.J. Postnatal growth and development in the preterm and small for gestational age infants. Nestle Nutr Inst Workshop Ser Pediat Program 2010; 65: 85–98.
8. Franz A.R., Pohlandt F., Bode H. Intrauterine, early neonatal, and postdischarge growth and neurodevelopmental outcome at 5,4 years in extremely preterm infants after intensive neonatal nutrition support. Pediatrics 2009; 123: e101–109.
9. Rosenbaum P., Paneth N., Leviton A. et al. A report: the definition and classification of cerebral palsy. Dev Med Child Neurol 2007; 109: 8–14.
10. Vohr B.R., Wright L.L., Pole W.K., McDonald S.A. Neurodevelopmental outcomes of extremely low birth weight infants <32 weeks’ gestation between 1993 and 1998. Pediatrics 2005; 116: 635–643.
11. Байбарина Е.Н., Антонов А.Г., Ионов О.В. Раннее применение назального СДППД с вариабельным потоком у недоношенных со сроком гестации 28–32 недели. Интенсивная терапия 2006; 2: http://www.icjcorp.ru/2006-02-06. html (Baybarina E.N., Antonov A.G., Ionov O.V. Early use of NCPAP with variable flow in premature babies with gestational age 28–32 weeks. Intensivnaya terapiya 2006, 2, http:// www.icjcorp.ru/2006-02-06.html)
12. Мазманян П.А., Саркисян Е А. Неинвазивная вентиляция легких у недоношенных новорожденных опыт использования методики СДППД (CPAP) в неонатальном отделении перинатального центра. Медицина критических состояний 2008; 1: 43–47. (Mazmanyan P.A., Sarkisyan E.A. Non-invasive lung ventilation in premature newborns – the experience of use of CPAP in neonatal intensive care unit of perinatal centre. Medicina kriticheskih sostoyanii 2008; 1: 43–47.)
13. Овсянников Д.Ю. Система оказания медицинской помощи детям, страдающим бронхолегочной дисплазией. Руководство для практикующих врачей. М 2010; 248. (Ovsyannikov D.Y. The system of medical assistance in children with bronchopulmonary dysplasia. The Manual for practice medicines. Moscow 2010; 248.)
14. Рюмина И.И., Яковлева М.М. Особенности вскармливания недоношенных детей. Рус мед журн 2011; 19: 3: 146– 149. (Ryumina I.I. Yakovleva M.M. Feeding trends of premature babies. Rus med zhurn 2011; 19: 3: 146–149.)
15. Суржик А.В. Современные продукты для вскармливания недоношенных детей. Педиатрическая фармакол 2012; 9: 4: 106–110. (Surdgik A.V. The modern products for premature babies feeding. Pediatricheskaya farmakol 2012; 9: 4: 106–110.)
16. Bloom B.T., Mulligan J., Arnold C. et al. Improving growth of very low birth weight infants in the first 28 days. Pediatrics 2003; 112: 8–14.
17. Ancel P., Livinec F., Larroque B., Epipage Study Group. Cerebral palsy among very preterm children in relation to gestational age and neonatal ultrasound abnormalities: the EPIPAGE cohort study. Pediatrics 2006; 117: 828–835.
18. Нетребенко Э.Л. Отдаленные последствия характера вскармливания детей на ранних этапах развития. Педиатрия 2005; 5: 29–32. (Netrebenko E.L. Long term effects of child nutrition in early months of life. Pediatriya 2005; 5: 29–32.)
19. Platt M., Cans C., Johnson A. et al. Trends in cerebral palsy among infants of very low birth weight (<1500g) or born prematurely (<32weeks) in 16 European centers: a data based study. Lancet 2007; 369: 43–50.
20. Checchia P.A., Nalysnyk L., Fernandes A.W. et al. Mortality and morbidity among infants at high risk for severe respiratory syncytial virus infection receiving prophylaxis with palivizumab: a systematic literature review and meta-analysis. Pediat Crit Care Med 2011; 12: 5: 580–588.
21. Ленюшкина А.А., Антонов А.Г., Байбарина Е.Н. и др. Современные аспекты нутритивной поддержки новорожденных с очень низкой и экстремально низкой массой тела в неонатальном периоде. Акуш и гин 2012; 6: 74–80. (Lenyushkina A.A., Antonov A.G., Baybarina E.N. et al. Current aspects of nutrition in premature newborns with very low and extremely low birth weight. Akysh i gin 2012; 6: 74–80.)
Review
For citations:
Sakharova E.S., Keshishian E.S., Alyamovskaya G.A. Trends in morbidity rates and developmental outcomes by 3 years of life in premature children followed up in a specialized center. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2015;60(3):108-112. (In Russ.)
Views:
1220
Email this article 