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Cerebral blood flow indices in children and adolescents with hypertension and metabolic syndrome

https://doi.org/10.21508/1027-4065-2016-61-3-58-64

Abstract

A total of 141 patients aged 10 to 17 years were examined. Doppler ultrasonography was carried out to assess blood flow in the intracranial (basilar and middle cerebral arteries) and extracranial (common and internal carotid arteries, vertebral arteries) cerebral arteries and cerebral vein (tentorial venous sinus) and the velocity characteristics of the flow and the level of peripheral vascular resistance were analyzed in all the children. Normal weight children with stable hypertension were found to have high peripheral vascular resistance in the beds of intracranial (basilar and right middle cerebral arteries) and extracranial arteries with the phenomena of hyperperfusion in the bed of the common carotid artery. Obese children having different stages of hypertension were, on the contrary, observed to have lowered peripheral resistance in the intracranial arteries and increased peak systolic blood flow velocity in the tentorial venous sinus. The found cerebral hemodynamic differences may suggest that obese children have secondary hypertension.

About the Authors

S. Yu. Novikov
N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Russian Federation
Moscow


I. G. Moreno
N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Russian Federation
Moscow


P. V. Shumilov
N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Russian Federation
Moscow


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For citations:


Novikov S.Yu., Moreno I.G., Shumilov P.V. Cerebral blood flow indices in children and adolescents with hypertension and metabolic syndrome. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2016;61(3):58-64. (In Russ.) https://doi.org/10.21508/1027-4065-2016-61-3-58-64

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ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)