Инфекции, вызванные вирусами герпеса 6-го типа: современные особенности


https://doi.org/10.21508/1027-4065-2016-61-5-127-131

Полный текст:


Аннотация

Представлен обзор современных сведений об этиологии, эпидемиологии, клинических проявлениях инфекции, вызванной вирусами герпеса 6-го типа у детей и взрослых, рассмотрены вопросы диагностики с использованием лабораторных методов исследования и принципы лечения данной патологии. 


Об авторах

В. А. Анохин
ГБОУ ВПО «Казанский государственный медицинский университет им. С.В. Курашова» Минздрава РФ, Казань
Россия

кафедра детских инфекций

д.м.н., проф., зав. кафедрой 

главный детский инфекционист Минздрава Республики Татарстан 

420012 Казань, ул. Бутлерова, д. 49



А. М. Сабитова
ГБОУ ВПО «Казанский государственный медицинский университет им. С.В. Курашова» Минздрава РФ, Казань
Россия

кафедра детских инфекций

к.м.н., доцент 

420012 Казань, ул. Бутлерова, д. 49



Список литературы

1. Salahuddin S.Z., Ablashi D.V., Markham P.D. et al. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science 1986; 234: 596.

2. Ablashi D.V., Salahuddin S.Z., Josephs S.F. et al. HBLV (or HHV-6) in human cell lines. Nature 1987; 329: 207.

3. Yamanishi K., Okuno T., Shiraki K. et al. Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet 1988; 1: 1065.

4. International Committee on Taxonomy of Viruses. ICTV Master Species List 2011. http://talk.ictvonline.org/files/ ictv_documents/m/msl/4090.aspx (Accessed on June 27, 2012).

5. Hall C.B., Long C.E., Schnabel K.C. et al. Human herpesvirus-6 infection in children. A prospective study of complications and reactivation. N Engl J Med 1994; 331: 432.

6. Tremblay C. Virology, pathogenesis, and epidemiology of human herpesvirus 6 infection. 2016; 24.168: http://www.uptodate.com

7. Kondo K., Kondo T., Shimada K. et al. Strong interaction between human herpesvirus 6 and peripheral blood monocytes/macrophages during acute infection. J Med Virol 2002; 67: 364.

8. Di Luca D., Mirandola P., Ravaioli T. et al. Human herpesviruses 6 and 7 in salivary glands and shedding in saliva of healthy and human immunodeficiency virus positive individuals. J Med Virol 1995; 45: 462.

9. Dockrell D.H., Paya C.V. Human herpesvirus-6 and -7 in transplantation. Rev Med Virol 2001; 11: 1: 23.

10. Tremblay C. Clinical manifestations, diagnosis, and treatment of human herpesvirus 6 infection in adults, 2016; 24.159: http://www.uptodate.com 11. Ogata M., Satou T., Kadota J. et al. Human herpesvirus 6 (HHV-6) reactivation and HHV-6 encephalitis after allogeneic hematopoietic cell transplantation: a multicenter, prospective study. Clin Infect Dis 2013; 57: 671.

11. Aihara Y., Ito S.I., Kobayashi Y. et al. Carbamazepine-induced hypersensitivity syndrome associated with transient hypogammaglobulinaemia and reactivation of human herpesvirus 6 infection demonstrated by real-time quantitative polymerase chain reaction. Br J Dermatol 2003; 149: 165.

12. Oskay T., Karademir A., Ertürk O.I. Association of anticon￾vulsant hypersensitivity syndrome with Herpesvirus 6, 7. Epilepsy Res 2006; 70: 27.

13. Tamagawa-Mineoka R., Katoh N., Nara T. et al. DRESS syndrome caused by teicoplanin and vancomycin, associated with reactivation of human herpesvirus-6. Int J Dermatol 2007; 46: 654.

14. Morimoto T., Sato T., Matsuoka A. et al. Trimethoprim-sulfamethoxazole-induced hypersensitivity syndrome associated with reactivation of human herpesvirus-6. Intern Med 2006; 45: 101.

15. Tremblay C., Brady M. Human herpesvirus 6 infection in children: Clinical manifestations; diagnosis; and treatment. 2016; 24.168: http://www.uptodate.com

16. Rotola A., Merlotti I., Caniatti L. et al. Human herpesvirus 6 infects the central nervous system of multiple sclerosis patients in the early stages of the disease. Mult Scler 2004; 10: 348.

17. Luppi M., Marasca R., Barozzi P. et al. Three cases of human herpesvirus-6 latent infection: integration of viral genome in peripheral blood mononuclear cell DNA. J Med Virol 1993; 40: 1: 44.

18. Morissette G., Flamand L. Herpesviruses and chromosomal integration. J Virol 2010; 84: 23: 12100.

19. Никольский М.А., Голубцова В.С. Хромосомно-интегрированный вирус герпеса человека 6-го типа. Инфекция и иммунитет 2015; 5: 1: 7. (Nikolsky M.A., Golubtsova V.S. Chromosomally-integrated human herpes virus type 6. Infektsiya i immunitet 2015; 5: 1: 7. (in Russ))

20. Jeulin H., Salmon A., Gautheret-Dejean A. et al. Contribution of human herpesvirus 6 (HHV-6) viral load in whole blood and serum to investigate integrated HHV-6 transmission after haematopoietic stem cell transplantation. J Clin Virol 2009; 45: 43.

21. Ward K.N., Leong H.N., Nacheva E.P. et al. Human herpesvirus 6 chromosomal integration in immunocompetent patients results in high levels of viral DNA in blood, sera, and hair follicles. J Clin Microbiol 2006; 44: 4: 1571.

22. Caserta M.T., Hall C.B., Canfield R.L. et al. Early developmental outcomes of children with congenital HHV-6 infection. Pediatrics 2014; 134: 1111.

23. Ashshi A.M., Cooper R.J., Klapper P.E. et al. Detection of human herpes virus 6 DNA in fetal hydrops. Lancet 2000; 355: 1519.

24. Asano Y., Yoshikawa T., Suga S. et al. Fatal fulminant hepatitis in an infant with human herpesvirus-6 infection. Lancet 1990; 335: 862.

25. Muramatsu H., Watanabe N., Matsumoto K. et al. Primary infection of human herpesvirus-6 in an infant who received cord blood SCT. Bone Marrow Transplant 2009; 43: 83.

26. Hall C.B., Caserta M.T., Schnabel K.C. et al. Congenital infections with human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7). J Pediatr 2004; 145: 472.

27. Кускова Т.К., Белова Е.Г. Семейство герпесвирусов на современном этапе. Лечащий врач 2004; 5: 611. (Kuskova T.K., Belova E.G. The family of herpes viruses at the present stage. Lechashhij vrach 2004; 5: 611. (in Russ))

28. Freitas R.B., Monteiro T.A., Linhares A.C. Outbreaks of humanherpes virus 6 (HHV-6) infection in day-care centers in Belém, Pará, Brazil. Rev Inst Med Trop Sao Paulo 2000; 42: 305.

29. Zerr D.M., Meier A.S., Selke S.S. et al. A population-based study of primary human herpesvirus 6 infection. N Engl J Med 2005; 352: 768.

30. American Academy of Pediatrics. Human herpesvirus 6 (including roseola) and 7. In: Red Book: 2015 Report of the Committee on Infectious Diseases. D.W. Kimberlin, M.T. Brady, M.A. Jackson, S.S. Long (Eds). American Academy of Pediatrics, Elk Grove Village, IL, 2015; 449.

31. Tremblay C., Brady M. Roseola infantum (exanthem subi￾tum). 2016; 24.168 (http://www.uptodate.com).

32. Vianna R.A., de Oliveira S.A., Camacho L.A. et al. Role of human herpesvirus 6 infection in young Brazilian children with rash illnesses. Pediatr Infect Dis J 2008; 27: 533.

33. Laina I., Syriopoulou V.P., Daikos G.L. et al. Febrile seizures and primary human herpesvirus 6 infection. Pediatr Neurol 2010; 42: 28.

34. Никольский М.А., Радыш М.В. Роль вирусов герпеса человека 6-го и 7-го типов в возникновении фебрильных судорог у детей. Вопросы диагностики в педиатрии 2012; 4: 4: 46. (Nikolsky M.A., Radysh M.V. The role of human herpes virus 6 and the seventh type occurs in febrile convulsions in children. Voprosy diagnostiki v pediatrii 2012; 4: 4: 46. (in Russ))

35. Huang C.T., Lin L.H. Differentiating roseola infantum with pyuria from urinary tract infection. Pediatr Int 2013; 55: 214.

36. Rohayem J., Dinger J., Fischer R. et al. Fatal myocarditis associated with acute parvovirus B19 and human herpesvirus 6 coinfection. J Clin Microbiol 2001; 39: 4585.

37. Mannonen L., Herrgård E., Valmari P. et al. Primary human herpesvirus-6 infection in the central nervous system can cause severe disease. Pediatr Neurol 2007; 37: 186.

38. Crawford J.R., Kadom N., Santi M.R. et al. Human herpesvirus 6 rhombencephalitis in immunocompetent children. J Child Neurol 2007; 22: 1260.

39. Ohsaka M., Houkin K., Takigami M., Koyanagi I. Acute necrotizing encephalopathy associated with human herpesvirus-6 infection. Pediatr Neurol 2006; 34: 160.

40. Fotheringham J., Donati D., Akhyani N. et al. Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS Med 2007; 4: e180.

41. Kawabe S., Ito Y., Ohta R. et al. Comparison of the levels of human herpesvirus 6 (HHV-6) DNA and cytokines in the cerebrospinal fluid and serum of children with HHV-6 encephalopathy. J Med Virol 2010; 82: 1410.

42. Hammerling J.A., Lambrecht R.S., Kehl K.S., Carrigan D.R. Prevalence of human herpesvirus 6 in lung tissue from children with pneumonitis. J Clin Pathol 1996; 49: 802.

43. Kanegane C., Katayama K., Kyoutani S. et al. Mononucleosislike illness in an infant associated with human herpesvirus 6 infection. Acta Paediatr Jpn 1995; 37: 227.

44. Fretzayas A., Douros K., Moustaki M., Nicolaidou P. Papularpurpuric gloves and socks syndrome in children and adoles￾cents. Pediatr Infect Dis J 2009; 28: 250.

45. Chuh A.A., Chan H.H., Chiu S.S. et al. A prospective case control study of the association of Gianotti-Crosti syndrome with human herpesvirus 6 and human herpesvirus 7 infections. Pediatr Dermatol 2002; 19: 492.

46. Boccara O., Lesage F., Regnault V. et al. Nonbacterial purpura fulminans and severe autoimmune acquired protein S deficiency associated with human herpesvirus-6 active replication. Br J Dermatol 2009; 161: 181.

47. Miyake F., Yoshikawa T., Suzuki K. et al. Guillain-Barré syndrome after exanthem subitum. Pediatr Infect Dis J 2002; 21: 569.

48. Pitkäranta A., Lahdenne P., Piiparinen H. Facial nerve palsy after human herpesvirus 6 infection. Pediatr Infect Dis J 2004; 23: 688.

49. Nishimura N., Yoshikawa T., Ozaki T. et al. In vitro and in vivo analysis of human herpesvirus-6 U90 protein expression. J Med Virol 2005; 75: 86.

50. Никольский М.А., Мессорош В.Г., Минченко С.И. Сероконверсия и нарастание концентрации IgG-антител при инфекции, вызванной вирусом герпеса 6-го типа у детей. Эпидемиология и инфекционные болезни 2008; 4: 22. (Nikolsky M.A., Messorosh V.G., Minchenko S.I. Seroconversion and increase in the concentration of IgG antibodies against infections caused by the herpes virus type 6 children. EHpidemiologiya i infektsionnye bolezni 2008; 4: 22. (in Russ))

51. Fujiwara N., Namba H., Ohuchi R. et al. Monitoring of human herpesvirus-6 and -7 genomes in saliva samples of healthy adults by competitive quantitative PCR. J Med Virol 2000; 61: 208.

52. Caserta M.T., McDermott M. P., Dewhurst S. et al. Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children. J Pediatr 2004; 145: 478.

53. Flamand L., Gravel A., Boutolleau D. et al. Multicenter comparison of PCR assays for detection of human herpesvirus 6 DNA in serum. J Clin Microbiol 2008; 46: 2700.

54. Reddy S., Manna P. Quantitative detection and differentiation of human herpesvirus 6 subtypes in bone marrow transplant patients by using a single real-time polymerase chain reaction assay. Biol Blood Marrow Transplant 2005; 11: 530.

55. Zerr D.M., Boeckh M., Delaney C. et al. HHV-6 reactivation and associated sequelae after hematopoietic cell transplantation. Biol Blood Marrow Transplant 2012; 18: 1700.

56. Caserta M.T., Hall C.B., Schnabel K. et al. Diagnostic assays for active infection with human herpesvirus 6 (HHV-6). J Clin Virol 2010; 48: 55.

57. De Bolle L., Naesens L., De Clercq E. Update on human herpesvirus 6 biology, clinical features, and therapy. Clin Microbiol Rev 2005; 18: 217.

58. Zerr D.M., Gupta D., Huang M.L. et al. Effect of antivirals on human herpesvirus 6 replication in hematopoietic stem cell transplant recipients. Clin Infect Dis 2002; 34: 309.

59. Denes E., Magy L., Pradeau K. et al. Successful treatment of human herpesvirus 6 encephalomyelitis in immunocompetent patient. Emerg Infect Dis 2004; 10: 729.


Дополнительные файлы

Для цитирования: Анохин В.А., Сабитова А.М. Инфекции, вызванные вирусами герпеса 6-го типа: современные особенности. Российский вестник перинатологии и педиатрии. 2016;61(5):127-131. https://doi.org/10.21508/1027-4065-2016-61-5-127-131

For citation: Anokhin V.A., Sabitova A.M. Infections caused by herpes virus type 6: modern features. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2016;61(5):127-131. (In Russ.) https://doi.org/10.21508/1027-4065-2016-61-5-127-131

Просмотров: 263

Обратные ссылки

  • Обратные ссылки не определены.


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)