New approaches to the prevention of recurrent respiratory diseases in preschool age
https://doi.org/10.21508/1027-4065-2019-64-4-65-69
Abstract
Objective. To evaluate the effectiveness of the natural terpenoids complex in preschool children with recurrent acute respiratory infections (ARI).
Material and methods. There were examined 7129 children of 3-7 years old, they were divided into 3 groups. In main group (n = 2400) there was endonasally (on the mucous membrane of the nasal cavity with cotton buds) used a complex of natural terpenoids 2 times a day (morning and evening) 5 days a week for 1 - 3 months. Prevention and treatment of children from the comparison group (n = 2,379) was carried out with dioxotetrahydroxy tetrahydronaphthalene. The control group consisted of children (n = 2,350), who received no therapy. Upon completion of the course of therapy, children were examined in dynamics.
Results. The authors noted positive clinical effect of the natural terpenoid complex, as evidenced by a 1.6 times decrease in acute respiratory infections during the year and the duration of the acute episode of the disease by 2.5 days, as well as a positive effect on the elimination of Epstein Barr virusin frequently ill children when using drug for 65.51 ± 2.98 days. The authors observed a favorable clinical effect against the decrease in neutrophils and eosinophils in the rhinocytogram, as well as mixed flora and cocci, indicating a decrease in mucosal neutrophilic inflammation and prevention of bacterial complications.
Supporting agencies: This work was supported by Ltd «Initi-Advance».
About the Authors
V. N. Krasnozhen
Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education
Russian Federation
Kazan
Russian Federation
Kazan
A. M. Zakirova
Kazan State Medical University
Russian Federation
Kazan
Russian Federation
Kazan
T. G. Malanicheva
Kazan State Medical University
Russian Federation
Kazan
Russian Federation
Kazan
E. L. Rashitovа
Kazan State Medical University
Russian Federation
Kazan
Russian Federation
Kazan
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Review
For citations:
Krasnozhen V.N., Zakirova A.M., Malanicheva T.G., Rashitovа E.L. New approaches to the prevention of recurrent respiratory diseases in preschool age. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2019;64(4):65-69. (In Russ.) https://doi.org/10.21508/1027-4065-2019-64-4-65-69
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